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1-303-522-8502 
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Online Inquiry 1-303-522-8502 :[email protected]
| Product Name | SBE-Luc/HEK293 Reporter Cell Line |
| Cat.No | RG-587 |
| Size | 1*10^6 cells/vial |
| Description | The SBE-Luc/HEK293 Reporter Cell Line is designed for monitoring the activity of the TGF /SMAD signaling pathway. The transforming growth factor beta (TGF) signaling pathway is involved in a diverse range of cell processes such as differentiation, cell cycle arrest, and immune regulation. TGF signaling has been linked to cardiac disease, cancer, Alzheimer’s and other human diseases. TGF proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to phosphorylation and activation of SMAD2 and SMAD3, which then form a complex with SMAD4. The SMAD complex then translocates to the nucleus and binds to the SMAD binding element (SBE) in the nucleus, leading to transcription and expression of TGF / SMAD responsive genes. |
| Species | Homo sapiens, human |
| Full Name | SBE-Luc/HEK293 Reporter Cell Line, SBE-Luc/HEK293 |
| Parental Cell Line | HEK293 |
| Biosafety Level | BSL 2. Runtogen determines the biosafety level of a material based on our risk assessment as guided by the current edition of Biosafety in Microbiological and Biomedical Laboratories (BMBL), U.S. Department of Health and Human Services. |
| Expression Gene | Luciferase |
| Culture Method | DMEM+10%FBS+100ug/ml hygromycin |
| Quality Control | SBE-Luc/HEK293 Reporter Cell Line is negative for mycoplasma, bacteria, yeast, and fungi. |
| Shipping | Cryopreserved cells are shipped with dry ice |
| Storage | Upon arrival, Check all containers for leakage or breakage. Remove the frozen cells from the dry ice packaging and immediately place the cells at a temperature below -130°C, preferably in liquid nitrogen vapor, until ready for use. |
| Warranty | SBE-Luc/HEK293 Reporter Cell Line is warranted for 30 days from the date of shipment, provided that the customer has stored and handled the product according to the information included on the product datasheet, website, and COA. |
| Disclaimers | This cell line is intended for laboratory research use only. It is not intended for any human or animal therapeutic use, any animal or human consumption, or any diagnostic use. Any proposed commercial use is prohibited without a license from Runtogen. |
Inquire the SBE-Luc/HEK293 Reporter Cell Line by filling out the form below. We’ll get back to you within 24 hours with a quote.
Inquire the SBE-Luc/HEK293 Reporter Cell Line by filling out the form below. We’ll get back to you within 24 hours with a quote.
