Kinase Cell Lines
A kinase cell line is a cell line that can be used to study kinases, which are enzymes that regulate cell growth and proliferation. Some examples of kinase cell lines include:
Ba/F3
A murine pro-B cell line that can proliferate without IL-3 due to the overexpression of specific kinases. Ba/F3 cells are a popular model system for assessing the potency of kinase oncogenes and the ability of kinase inhibitors to block kinase activity.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human cell line that can be used to study thymidine kinase 1.
Kinases are part of the phosphotransferase family of enzymes, and they play a critical role in phosphorylation, a process that produces a phosphorylated substrate and ADP. Kinases alter the activity, expression, or localization of proteins by altering their phosphorylation.
Runtogen offers more than 1.000 human and BA/F3 kinase cell lines, encompassing various signaling pathways such as EGFR, VEGFR, FGFR, ERBB2, ERBB3, PDGFR, Kit, ABL, AKT1, TPR, MPL, KRAS, and more.
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NIH/3T3-BRAF-L597R Cell Line
Catalog#: RG-676
Size: 5*10^6 cells/vial
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NIH/3T3-BRAF-L597V Cell Line
Catalog#: RG-677
Size: 5*10^6 cells/vial
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NIH/3T3-BRAF-V487-P492DelinsA Cell Line
Catalog#: RG-678
Size: 5*10^6 cells/vial
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NIH/3T3-cKit-AY502-3dup Cell Line
Catalog#: RG-679
Size: 5*10^6 cells/vial
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NCI-H1975 EGFR-H773_V774insNPH Cell Line
Catalog#: RG-664
Size: 5*10^6 cells/vial
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NIH/3T3-CLIP1-LTK-F568C Cell Line
Catalog#: RG-680
Size: 5*10^6 cells/vial
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NCI-H1975-EGFR-D770-N771insSVD Cell Line
Catalog#: RG-665
Size: 5*10^6 cells/vial
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NIH/3T3-CLIP1-LTK-G596R Cell Line
Catalog#: RG-681
Size: 5*10^6 cells/vial
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NCI-H1975-EGFR-L858R-T790M-C797S Cell Line
Catalog#: RG-666
Size: 5*10^6 cells/vial
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