Kinase Cell Lines
A kinase cell line is a cell line that can be used to study kinases, which are enzymes that regulate cell growth and proliferation. Some examples of kinase cell lines include:
Ba/F3
A murine pro-B cell line that can proliferate without IL-3 due to the overexpression of specific kinases. Ba/F3 cells are a popular model system for assessing the potency of kinase oncogenes and the ability of kinase inhibitors to block kinase activity.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human cell line that can be used to study thymidine kinase 1.
Kinases are part of the phosphotransferase family of enzymes, and they play a critical role in phosphorylation, a process that produces a phosphorylated substrate and ADP. Kinases alter the activity, expression, or localization of proteins by altering their phosphorylation.
Runtogen offers more than 1.000 human and BA/F3 kinase cell lines, encompassing various signaling pathways such as EGFR, VEGFR, FGFR, ERBB2, ERBB3, PDGFR, Kit, ABL, AKT1, TPR, MPL, KRAS, and more.
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Catalog#: RG-330
Size: 1*10^6 cells/vial
Gene Name:
c-Kit
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Ba/F3-CCDC6-RET WT Cell Line
Catalog#: RG-346
Size: 1*10^6 cells/vial
Gene Name:
CCDC6
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Ba/F3-c-Kit K642E-D816A Cell Line
Catalog#: RG-331
Size: 1*10^6 cells/vial
Gene Name:
c-Kit
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Ba/F3-CCDC6-RET [V804L] Cell Line
Catalog#: RG-347
Size: 1*10^6 cells/vial
Gene Name:
CCDC6
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Catalog#: RG-332
Size: 1*10^6 cells/vial
Gene Name:
c-Kit
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Ba/F3-CCDC6-RET [V804M] Cell Line
Catalog#: RG-348
Size: 1*10^6 cells/vial
Gene Name:
CCDC6
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Catalog#: RG-333
Size: 1*10^6 cells/vial
Gene Name:
c-Kit
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Catalog#: RG-334
Size: 1*10^6 cells/vial
Gene Name:
c-Kit
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Catalog#: RG-335
Size: 1*10^6 cells/vial
Gene Name:
c-Kit
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