Kinase Cell Lines
A kinase cell line is a cell line that can be used to study kinases, which are enzymes that regulate cell growth and proliferation. Some examples of kinase cell lines include:
Ba/F3
A murine pro-B cell line that can proliferate without IL-3 due to the overexpression of specific kinases. Ba/F3 cells are a popular model system for assessing the potency of kinase oncogenes and the ability of kinase inhibitors to block kinase activity.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human cell line that can be used to study thymidine kinase 1.
Kinases are part of the phosphotransferase family of enzymes, and they play a critical role in phosphorylation, a process that produces a phosphorylated substrate and ADP. Kinases alter the activity, expression, or localization of proteins by altering their phosphorylation.
Runtogen offers more than 1.000 human and BA/F3 kinase cell lines, encompassing various signaling pathways such as EGFR, VEGFR, FGFR, ERBB2, ERBB3, PDGFR, Kit, ABL, AKT1, TPR, MPL, KRAS, and more.
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NIH/3T3-cMet-Del14-Y1230H Cell Line
Catalog#: RG-693
Size: 5*10^6 cells/vial
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NIH/3T3-EML4-ALK-C1156Y-G1296A Cell Line
Catalog#: RG-694
Size: 5*10^6 cells/vial
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NIH/3T3-EML4-ALK-F1174C-G1202R Cell Line
Catalog#: RG-695
Size: 5*10^6 cells/vial
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NIH/3T3-EML4-ALK-F1174L-G1202R Cell Line
Catalog#: RG-696
Size: 5*10^6 cells/vial
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NIH/3T3-EML4-ALK-L1196M-D1203N Cell Line
Catalog#: RG-697
Size: 5*10^6 cells/vial
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NIH/3T3-ETV6-BTK-C481S Cell Line
Catalog#: RG-698
Size: 5*10^6 cells/vial
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NIH/3T3-ETV6-FGFR3 Cell Line
Catalog#: RG-699
Size: 5*10^6 cells/vial
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NIH/3T3-CLIP1-LTK-L590M Cell Line
Catalog#: RG-684
Size: 5*10^6 cells/vial
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NIH/3T3-FGFR2-BICC1-C491S Cell Line
Catalog#: RG-700
Size: 5*10^6 cells/vial
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