Kinase Cell Lines
A kinase cell line is a cell line that can be used to study kinases, which are enzymes that regulate cell growth and proliferation. Some examples of kinase cell lines include:
Ba/F3
A murine pro-B cell line that can proliferate without IL-3 due to the overexpression of specific kinases. Ba/F3 cells are a popular model system for assessing the potency of kinase oncogenes and the ability of kinase inhibitors to block kinase activity.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human cell line that can be used to study thymidine kinase 1.
Kinases are part of the phosphotransferase family of enzymes, and they play a critical role in phosphorylation, a process that produces a phosphorylated substrate and ADP. Kinases alter the activity, expression, or localization of proteins by altering their phosphorylation.
Runtogen offers more than 1.000 human and BA/F3 kinase cell lines, encompassing various signaling pathways such as EGFR, VEGFR, FGFR, ERBB2, ERBB3, PDGFR, Kit, ABL, AKT1, TPR, MPL, KRAS, and more.
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Catalog#: RG-419
Size: 1*10^6 cells/vial
Gene Name:
EZR
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Ba/F3-FGFR2-AHCYL1 Cell Line
Catalog#: RG-420
Size: 1*10^6 cells/vial
Gene Name:
FGFR2
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Catalog#: RG-421
Size: 1*10^6 cells/vial
Gene Name:
FGFR2
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Ba/F3-FGFR3-TACC3 [K650N] Cell Line
Catalog#: RG-422
Size: 1*10^6 cells/vial
Gene Name:
FGFR3
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Ba/F3-FLT3-ITD [D835del] Cell Line
Catalog#: RG-423
Size: 1*10^6 cells/vial
Gene Name:
FLT3
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Ba/F3-FLT3-ITD [D835E] Cell Line
Catalog#: RG-424
Size: 1*10^6 cells/vial
Gene Name:
FLT3
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Ba/F3-EML4-ALK V1 [L1198F] Cell Line
Catalog#: RG-409
Size: 1*10^6 cells/vial
Gene Name:
EML4
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Ba/F3-FLT3-ITD [D835H] Cell Line
Catalog#: RG-425
Size: 1*10^6 cells/vial
Gene Name:
FLT3
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Catalog#: RG-410
Size: 1*10^6 cells/vial
Gene Name:
EML4
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