Kinase Cell Lines
A kinase cell line is a cell line that can be used to study kinases, which are enzymes that regulate cell growth and proliferation. Some examples of kinase cell lines include:
Ba/F3
A murine pro-B cell line that can proliferate without IL-3 due to the overexpression of specific kinases. Ba/F3 cells are a popular model system for assessing the potency of kinase oncogenes and the ability of kinase inhibitors to block kinase activity.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human cell line that can be used to study thymidine kinase 1.
Kinases are part of the phosphotransferase family of enzymes, and they play a critical role in phosphorylation, a process that produces a phosphorylated substrate and ADP. Kinases alter the activity, expression, or localization of proteins by altering their phosphorylation.
Runtogen offers more than 1.000 human and BA/F3 kinase cell lines, encompassing various signaling pathways such as EGFR, VEGFR, FGFR, ERBB2, ERBB3, PDGFR, Kit, ABL, AKT1, TPR, MPL, KRAS, and more.
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Catalog#: RG-410
Size: 1*10^6 cells/vial
Gene Name:
EML4
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Ba/F3-FLT3-ITD [D835V] Cell Line
Catalog#: RG-426
Size: 1*10^6 cells/vial
Gene Name:
FLT3
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Ba/F3-EML4-ALK V3a Cell Line
Catalog#: RG-411
Size: 1*10^6 cells/vial
Gene Name:
EML4
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Ba/F3-FLT3-ITD [D835Y] Cell Line
Catalog#: RG-427
Size: 1*10^6 cells/vial
Gene Name:
FLT3
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Ba/F3-EML4-ALK V3b Cell Line
Catalog#: RG-412
Size: 1*10^6 cells/vial
Gene Name:
EML4
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Ba/F3-FLT3-ITD [F691L] Cell Line
Catalog#: RG-428
Size: 1*10^6 cells/vial
Gene Name:
FLT3
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Ba/F3-ERBB4 E452K (NRG1b Dependent) Cell Line
Catalog#: RG-413
Size: 1*10^6 cells/vial
Gene Name:
ERBB4
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Ba/F3-ERBB4 WT(NRG1b Dependent) Cell Line
Catalog#: RG-414
Size: 1*10^6 cells/vial
Gene Name:
ERBB4
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Ba/F3-ETV6(Tel)-ARG Cell Line
Catalog#: RG-415
Size: 1*10^6 cells/vial
Gene Name:
ETV6
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