Kinase Cell Lines
A kinase cell line is a cell line that can be used to study kinases, which are enzymes that regulate cell growth and proliferation. Some examples of kinase cell lines include:
Ba/F3
A murine pro-B cell line that can proliferate without IL-3 due to the overexpression of specific kinases. Ba/F3 cells are a popular model system for assessing the potency of kinase oncogenes and the ability of kinase inhibitors to block kinase activity.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human cell line that can be used to study thymidine kinase 1.
Kinases are part of the phosphotransferase family of enzymes, and they play a critical role in phosphorylation, a process that produces a phosphorylated substrate and ADP. Kinases alter the activity, expression, or localization of proteins by altering their phosphorylation.
Runtogen offers more than 1.000 human and BA/F3 kinase cell lines, encompassing various signaling pathways such as EGFR, VEGFR, FGFR, ERBB2, ERBB3, PDGFR, Kit, ABL, AKT1, TPR, MPL, KRAS, and more.
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Ba/F3-PDGFRA V658A-V561A Cell Line
Catalog#: RG-465
Size: 1*10^6 cells/vial
Gene Name:
PDGFRA
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Ba/F3-KRAS G12C-R68S Cell Line
Catalog#: RG-450
Size: 1*10^6 cells/vial
Gene Name:
KRAS
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Ba/F3-PDGFRA V658A Cell Line
Catalog#: RG-466
Size: 1*10^6 cells/vial
Gene Name:
PDGFRA
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Ba/F3-Her2 P780_Y781insGSP Cell Line
Catalog#: RG-435
Size: 1*10^6 cells/vial
Gene Name:
Her2
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Catalog#: RG-436
Size: 1*10^6 cells/vial
Gene Name:
Her2
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Catalog#: RG-437
Size: 1*10^6 cells/vial
Gene Name:
JAK2
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Ba/F3-KIF5B(E15)-RET(E12) [G810R] Cell Line
Catalog#: RG-438
Size: 1*10^6 cells/vial
Gene Name:
KIF5B
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Ba/F3-KIF5B(E15)-RET(E12) [V804E] Cell Line
Catalog#: RG-439
Size: 1*10^6 cells/vial
Gene Name:
KIF5B
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Ba/F3-KIF5B(E15)-RET(E12) [V804L] Cell Line
Catalog#: RG-440
Size: 1*10^6 cells/vial
Gene Name:
KIF5B
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