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Kinase Cell Lines

A kinase cell line is a cell line that can be used to study kinases, which are enzymes that regulate cell growth and proliferation. Some examples of kinase cell lines include: 
Ba/F3
A murine pro-B cell line that can proliferate without IL-3 due to the overexpression of specific kinases. Ba/F3 cells are a popular model system for assessing the potency of kinase oncogenes and the ability of kinase inhibitors to block kinase activity. 
K562
A human myeloid cell line that can be used to identify over- and under-active kinases. 
MOLM13/MV4–11
A human myeloid cell line that can be used to identify over- and under-active kinases. 
HEK293T
A human cell line that can be used to study thymidine kinase 1. 
Kinases are part of the phosphotransferase family of enzymes, and they play a critical role in phosphorylation, a process that produces a phosphorylated substrate and ADP. Kinases alter the activity, expression, or localization of proteins by altering their phosphorylation.
Runtogen offers more than 1.000 human and BA/F3 kinase cell lines, encompassing various signaling pathways such as EGFR, VEGFR, FGFR, ERBB2, ERBB3, PDGFR, Kit, ABL, AKT1, TPR, MPL, KRAS, and more.
  • Ba/F3-TPR-MET [F1200I] Cell Line

    Ba/F3-TPR-MET [F1200I] Cell Line

    Catalog#: RG-487
    Size: 1*10^6 cells/vial
    Gene Name: TPR-MET
  • Ba/F3-KRAS G12V Cell Line

    Ba/F3-KRAS G12V Cell Line

    Catalog#: RG-456
    Size: 1*10^6 cells/vial
    Gene Name: KRAS
  • Ba/F3-LMNA-NTRK1 Cell Line

    Ba/F3-LMNA-NTRK1 Cell Line

    Catalog#: RG-457
    Size: 1*10^6 cells/vial
    Gene Name: LMNA
  • Ba/F3-NACC2-NTRK2 Cell Line

    Ba/F3-NACC2-NTRK2 Cell Line

    Catalog#: RG-458
    Size: 1*10^6 cells/vial
    Gene Name: NACC2
  • Ba/F3-NCOA4-RET Cell Line

    Ba/F3-NCOA4-RET Cell Line

    Catalog#: RG-459
    Size: 1*10^6 cells/vial
    Gene Name: NCOA4
  • Ba/F3-PDGFRA D842V-G680R Cell Line

    Ba/F3-PDGFRA D842V-G680R Cell Line

    Catalog#: RG-460
    Size: 1*10^6 cells/vial
    Gene Name: PDGFRA
  • Ba/F3-PDGFRA D842V-T674I Cell Line

    Ba/F3-PDGFRA D842V-T674I Cell Line

    Catalog#: RG-461
    Size: 1*10^6 cells/vial
    Gene Name: PDGFRA
  • Ba/F3-PDGFRA D842V-V658A Cell Line

    Ba/F3-PDGFRA D842V-V658A Cell Line

    Catalog#: RG-462
    Size: 1*10^6 cells/vial
    Gene Name: PDGFRA
  • Ba/F3-PDGFRA D842V Cell Line

    Ba/F3-PDGFRA D842V Cell Line

    Catalog#: RG-463
    Size: 1*10^6 cells/vial
    Gene Name: PDGFRA