Kinase Cell Lines
A kinase cell line is a cell line that can be used to study kinases, which are enzymes that regulate cell growth and proliferation. Some examples of kinase cell lines include:
Ba/F3
A murine pro-B cell line that can proliferate without IL-3 due to the overexpression of specific kinases. Ba/F3 cells are a popular model system for assessing the potency of kinase oncogenes and the ability of kinase inhibitors to block kinase activity.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human myeloid cell line that can be used to identify over- and under-active kinases.
A human cell line that can be used to study thymidine kinase 1.
Kinases are part of the phosphotransferase family of enzymes, and they play a critical role in phosphorylation, a process that produces a phosphorylated substrate and ADP. Kinases alter the activity, expression, or localization of proteins by altering their phosphorylation.
Runtogen offers more than 1.000 human and BA/F3 kinase cell lines, encompassing various signaling pathways such as EGFR, VEGFR, FGFR, ERBB2, ERBB3, PDGFR, Kit, ABL, AKT1, TPR, MPL, KRAS, and more.
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HEK293T-Cynomolgus-ERBB3 Cell Line
Catalog#: RG-608
Size: 5*10^6 cells/vial
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HEK293T-Cynomolgus-FLT3 Cell Line
Catalog#: RG-609
Size: 5*10^6 cells/vial
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HEK293T-Cynomolgus-IGF1R-Low Cell Line
Catalog#: RG-610
Size: 5*10^6 cells/vial
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Ba/F3-TPR-MET [L1195F] Cell Line
Catalog#: RG-489
Size: 1*10^6 cells/vial
Gene Name:
TPR-MET
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Ba/F3-TPR-MET [Y1230C] Cell Line
Catalog#: RG-490
Size: 1*10^6 cells/vial
Gene Name:
TPR-MET
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Ba/F3-TPR-MET [Y1230H] Cell Line
Catalog#: RG-491
Size: 1*10^6 cells/vial
Gene Name:
TPR-MET
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Catalog#: RG-492
Size: 1*10^6 cells/vial
Gene Name:
TPR-MET
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Catalog#: RG-493
Size: 1*10^6 cells/vial
Gene Name:
TSLPR/IL7R
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Ba/F3-QKI-NTRK2 [G639R] Cell Line
Catalog#: RG-469
Size: 1*10^6 cells/vial
Gene Name:
QKI
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